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Figure 4 4.1 Therapeutic potential of probiotics in hypothyroidism: mechanistic insights The gut microbiota plays a key role in energy metabolism, and probiotics can optimize the structure of the gut microbiota and reshape the microecological balance (de Vos et al., 2022)

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Role of the gut microbiome in uremia: a potential therapeutic target

Generally, canonical Wnt cascades such as Wnt3a can stimulate insulin secretion and enhance the proliferation of cell by activating -catenin/TCF/LEF-mediated Cyclin D1 transcription

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